Syrvet Calf Boluses contain Antibodies, Probiotics, E.Coli, k99-Rotavirus 6 & 10, Coronavirus, Salmonella Dublin and Thyphimurium, Vitamins and Trace Minerals. Each biological component was selected for its symbiotic relationship with the calf gut microflora. All products are sage, natural biological products. Contains NO Medication , NO Withdrawal! Give 1-2 bolus as soon after birth as possible. On older calves 1-2 bolus as conditions warrent. Packaged 50 per jar.